Till startsida
University of Gothenburg
To content Read more about how we use cookies on gu.se

Neurodevelopment in Febrile Seizures and Childhood Epilepsy: Data from a Population-Based Swedish Twin Cohort

Participants: Colin Reilly, Sebastian Lundström , Elisabeth Fernell, Christopher Gillberg et al.

Background: There is a well-documented association between childhood epilepsy and ESSENCE but the relationship between febrile seizures (FS) and Early Symptomatic Syndromes Eliciting Neurodevelopmental Clinical Examinations (ESSENCE) is less clear. The majority of population-based studies have not shown an increase in ESSENCE type difficulties in FS, although one previous population-based study suggests a possible increase in ADHD in FS.

Methods: The Child and Adolescent Twin Study in Sweden (CATSS) is an ongoing population–based study targeting twins born in Sweden since July 1, 1992. This study involves:

• Parents of 27,092 twins being interviewed using a validated DSM-IV based interview (Autism-Tics, ADHD and other Comorbidities inventory, A-TAC) for ESSENCE, on their 9th or 12th birthday. ESSENCE problems considered were Autism Spectrum Disorder (ASD), Attention Deficit Hyperactivity Disorder (ADHD), Learning Difficulty (LD) and Developmental Coordination Disorder (DCD).
• Diagnoses of epilepsy (n=282) and FS (n=492) are based on the Swedish National Patient Register (NPR).
• Prevalence of ESSENCE in epilepsy and FS will be compared with prevalence in the total twin population.
• The association between FS and ESSENCE will be considered before and after adjustment for epilepsy.
• Age of diagnosis of FS/epilepsy will be considered as a possible correlate of ESSENCE in FS and epilepsy.

Results: Results will be available in 2017.

Page Manager: Anna Spyrou|Last update: 4/15/2016

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?